On the Estimation of Heritability with Family-Based and Population-Based Samples

For a family-based sample, the phenotypic variance-covariance matrix can be parameterized to include the variance of a polygenic effect that has then been estimated using a variance component analysis. However, with the advent of large-scale genomic data, the genetic relationship matrix (GRM) can be...

Descripción completa

Detalles Bibliográficos
Autores principales: Kim, Youngdoe, Lee, Young, Lee, Sungyoung, Kim, Nam Hee, Lim, Jeongmin, Kim, Young Jin, Oh, Ji Hee, Min, Haesook, Lee, Meehee, Seo, Hyeon-Jeong, Lee, So-Hyun, Sung, Joohon, Cho, Nam H., Kim, Bong-Jo, Han, Bok-Ghee, Elston, Robert C., Won, Sungho, Lee, Juyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538414/
https://www.ncbi.nlm.nih.gov/pubmed/26339629
http://dx.doi.org/10.1155/2015/671349

Ejemplares similares

Ejemplares similares