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Cyclometalated Iminophosphorane Gold(III) and Platinum(II) Complexes. A Highly Permeable Cationic Platinum(II) Compound with Promising Anticancer Properties
[Image: see text] New organometallic gold(III) and platinum(II) complexes containing iminophosphorane ligands are described. Most of them are more cytotoxic to a number of human cancer cell lines than cisplatin. Cationic Pt(II) derivatives 4 and 5, which differ only in the anion, Hg(2)Cl(6)(2–) or P...
Autores principales: | Frik, Malgorzata, Fernández-Gallardo, Jacob, Gonzalo, Oscar, Mangas-Sanjuan, Víctor, González-Alvarez, Marta, Serrano del Valle, Alfonso, Hu, Chunhua, González-Alvarez, Isabel, Bermejo, Marival, Marzo, Isabel, Contel, María |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538566/ https://www.ncbi.nlm.nih.gov/pubmed/26147404 http://dx.doi.org/10.1021/acs.jmedchem.5b00427 |
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