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Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium

Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography an...

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Autores principales: Habib, Zaiyad G., Dayyab, Farouq M., Sanda, Abdallah, Tambuwal, Sirajo H., Dalhat, Mahmood M., Muhammad, Hamza, Iliyasu, Garba, Nashabaru, Ibrahim, Habib, Abdulrazaq G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538769/
https://www.ncbi.nlm.nih.gov/pubmed/26339514
http://dx.doi.org/10.1155/2015/794109
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author Habib, Zaiyad G.
Dayyab, Farouq M.
Sanda, Abdallah
Tambuwal, Sirajo H.
Dalhat, Mahmood M.
Muhammad, Hamza
Iliyasu, Garba
Nashabaru, Ibrahim
Habib, Abdulrazaq G.
author_facet Habib, Zaiyad G.
Dayyab, Farouq M.
Sanda, Abdallah
Tambuwal, Sirajo H.
Dalhat, Mahmood M.
Muhammad, Hamza
Iliyasu, Garba
Nashabaru, Ibrahim
Habib, Abdulrazaq G.
author_sort Habib, Zaiyad G.
collection PubMed
description Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography and computed tomography showed widespread reticuloalveolar infiltrates and consolidation with cavitations, respectively. Both patients were Human Immunodeficiency Virus (HIV) seronegative and sputum smear negative for TB. Sputum GeneXpert MTB/Rif (Xpert MTB/RIF) was positive for Mycobacterium tuberculosis. To strengthen maternal and childhood TB control, screening with same-day point-of-care Xpert MTB/RIF is advocated among both HIV positive pregnant women and symptomatic HIV negative pregnant women during antenatal care in pregnancy and at puerperium.
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spelling pubmed-45387692015-09-03 Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium Habib, Zaiyad G. Dayyab, Farouq M. Sanda, Abdallah Tambuwal, Sirajo H. Dalhat, Mahmood M. Muhammad, Hamza Iliyasu, Garba Nashabaru, Ibrahim Habib, Abdulrazaq G. Case Rep Infect Dis Case Report Presentation of tuberculosis (TB) in pregnancy may be atypical with diagnostic challenges. Two patients with complicated pregnancy outcomes, foetal loss and live premature delivery at 5 and 7 months of gestation, respectively, and maternal loss, were diagnosed with pulmonary TB. Chest radiography and computed tomography showed widespread reticuloalveolar infiltrates and consolidation with cavitations, respectively. Both patients were Human Immunodeficiency Virus (HIV) seronegative and sputum smear negative for TB. Sputum GeneXpert MTB/Rif (Xpert MTB/RIF) was positive for Mycobacterium tuberculosis. To strengthen maternal and childhood TB control, screening with same-day point-of-care Xpert MTB/RIF is advocated among both HIV positive pregnant women and symptomatic HIV negative pregnant women during antenatal care in pregnancy and at puerperium. Hindawi Publishing Corporation 2015 2015-08-03 /pmc/articles/PMC4538769/ /pubmed/26339514 http://dx.doi.org/10.1155/2015/794109 Text en Copyright © 2015 Zaiyad G. Habib et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Habib, Zaiyad G.
Dayyab, Farouq M.
Sanda, Abdallah
Tambuwal, Sirajo H.
Dalhat, Mahmood M.
Muhammad, Hamza
Iliyasu, Garba
Nashabaru, Ibrahim
Habib, Abdulrazaq G.
Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title_full Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title_fullStr Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title_full_unstemmed Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title_short Role of GeneXpert MTB/Rif Assay in Diagnosing Tuberculosis in Pregnancy and Puerperium
title_sort role of genexpert mtb/rif assay in diagnosing tuberculosis in pregnancy and puerperium
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538769/
https://www.ncbi.nlm.nih.gov/pubmed/26339514
http://dx.doi.org/10.1155/2015/794109
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