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The AT-Hook motif as a versatile minor groove anchor for promoting DNA binding of transcription factor fragments

We report the development of chimeric DNA binding peptides comprising a DNA binding fragment of natural transcription factors (the basic region of a bZIP protein or a monomeric zinc finger module) and an AT-Hook peptide motif. The resulting peptide conjugates display high DNA affinity and excellent...

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Detalles Bibliográficos
Autores principales:	Rodríguez, Jéssica, Mosquera, Jesús, Couceiro, Jose R., Vázquez, M. Eugenio, Mascareñas, José L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Royal Society of Chemistry 2015
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538796/ https://www.ncbi.nlm.nih.gov/pubmed/26290687 http://dx.doi.org/10.1039/c5sc01415h

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