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Caffeine inhibits gene conversion by displacing Rad51 from ssDNA

Efficient repair of chromosomal double-strand breaks (DSBs) by homologous recombination relies on the formation of a Rad51 recombinase filament that forms on single-stranded DNA (ssDNA) created at DSB ends. This filament facilitates the search for a homologous donor sequence and promotes strand inva...

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Detalles Bibliográficos
Autores principales:	Tsabar, Michael, Mason, Jennifer M., Chan, Yuen-Ling, Bishop, Douglas K., Haber, James E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538809/ https://www.ncbi.nlm.nih.gov/pubmed/26019181 http://dx.doi.org/10.1093/nar/gkv525

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