Identification of in vivo DNA-binding mechanisms of Pax6 and reconstruction of Pax6-dependent gene regulatory networks during forebrain and lens development

The transcription factor Pax6 is comprised of the paired domain (PD) and homeodomain (HD). In the developing forebrain, Pax6 is expressed in ventricular zone precursor cells and in specific subpopulations of neurons; absence of Pax6 results in disrupted cell proliferation and cell fate specification...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Rockowitz, Shira, Xie, Qing, Ashery-Padan, Ruth, Zheng, Deyou, Cvekl, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538810/
https://www.ncbi.nlm.nih.gov/pubmed/26138486
http://dx.doi.org/10.1093/nar/gkv589

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538810/
https://www.ncbi.nlm.nih.gov/pubmed/26138486
http://dx.doi.org/10.1093/nar/gkv589

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