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FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma
Melanoma is the most aggressive skin cancer; its prognosis, particularly in advanced stages, is disappointing largely due to the resistance to conventional anticancer treatments and high metastatic potential. NF-κB constitutive activation is a major factor for the apoptosis resistance of melanoma. S...
Autores principales: | Romano, Simona, Xiao, Yichuan, Nakaya, Mako, D'Angelillo, Anna, Chang, Mikyoung, Jin, Jin, Hausch, Felix, Masullo, Mariorosario, Feng, Xixi, Romano, Maria Fiammetta, Sun, Shao-Cong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538817/ https://www.ncbi.nlm.nih.gov/pubmed/26101251 http://dx.doi.org/10.1093/nar/gkv615 |
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