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CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex

In order to catalyse the splicing of messenger RNA, multiple proteins and RNA components associate and dissociate in a dynamic highly choreographed process. The Prp19 complex is a conserved essential part of the splicing machinery thought to facilitate the conformational changes the spliceosome unde...

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Detalles Bibliográficos
Autores principales: van Maldegem, Febe, Maslen, Sarah, Johnson, Christopher M., Chandra, Anita, Ganesh, Karuna, Skehel, Mark, Rada, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538830/
https://www.ncbi.nlm.nih.gov/pubmed/26130721
http://dx.doi.org/10.1093/nar/gkv643