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CTNNBL1 facilitates the association of CWC15 with CDC5L and is required to maintain the abundance of the Prp19 spliceosomal complex
In order to catalyse the splicing of messenger RNA, multiple proteins and RNA components associate and dissociate in a dynamic highly choreographed process. The Prp19 complex is a conserved essential part of the splicing machinery thought to facilitate the conformational changes the spliceosome unde...
Autores principales: | van Maldegem, Febe, Maslen, Sarah, Johnson, Christopher M., Chandra, Anita, Ganesh, Karuna, Skehel, Mark, Rada, Cristina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538830/ https://www.ncbi.nlm.nih.gov/pubmed/26130721 http://dx.doi.org/10.1093/nar/gkv643 |
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