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Redefining the transcriptional regulatory dynamics of classically and alternatively activated macrophages by deepCAGE transcriptomics

Classically or alternatively activated macrophages (M1 and M2, respectively) play distinct and important roles for microbiocidal activity, regulation of inflammation and tissue homeostasis. Despite this, their transcriptional regulatory dynamics are poorly understood. Using promoter-level expression...

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Detalles Bibliográficos
Autores principales: Roy, Sugata, Schmeier, Sebastian, Arner, Erik, Alam, Tanvir, Parihar, Suraj P., Ozturk, Mumin, Tamgue, Ousman, Kawaji, Hideya, de Hoon, Michiel J. L., Itoh, Masayoshi, Lassmann, Timo, Carninci, Piero, Hayashizaki, Yoshihide, Forrest, Alistair R. R., Bajic, Vladimir B., Guler, Reto, Consortium, FANTOM, Brombacher, Frank, Suzuki, Harukazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538831/
https://www.ncbi.nlm.nih.gov/pubmed/26117544
http://dx.doi.org/10.1093/nar/gkv646