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Phosphatase and Tensin Homologue: Novel Regulation by Developmental Signaling

Phosphatase and tensin homologue (PTEN) is a critical cell endogenous inhibitor of phosphoinositide signaling in mammalian cells. PTEN dephosphorylates phosphoinositide trisphosphate (PIP(3)), and by so doing PTEN has the function of negative regulation of Akt, thereby inhibiting this key intracellu...

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Detalles Bibliográficos
Autor principal:	Jerde, Travis J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539077/ https://www.ncbi.nlm.nih.gov/pubmed/26339505 http://dx.doi.org/10.1155/2015/282567

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