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20(S)-ginsenoside Rg3 promotes senescence and apoptosis in gallbladder cancer cells via the p53 pathway

Gallbladder cancer (GBC), the most frequent malignancy of the biliary tract, is associated with high mortality and extremely poor prognosis. 20(S)-ginsenoside Rg3 (20(S)-Rg3) is a steroidal saponin with high pharmacological activity. However, the anticancer effect of 20(S)-Rg3 in human GBC has not y...

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Detalles Bibliográficos
Autores principales: Zhang, Fei, Li, Maolan, Wu, Xiangsong, Hu, Yunping, Cao, Yang, Wang, Xu’an, Xiang, Shanshan, Li, Huaifeng, Jiang, Lin, Tan, Zhujun, Lu, Wei, Weng, Hao, Shu, Yijun, Gong, Wei, Wang, Xuefeng, Zhang, Yong, Shi, Weibin, Dong, Ping, Gu, Jun, Liu, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539091/
https://www.ncbi.nlm.nih.gov/pubmed/26309394
http://dx.doi.org/10.2147/DDDT.S84527