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Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cy...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539193/ https://www.ncbi.nlm.nih.gov/pubmed/26281043 http://dx.doi.org/10.1371/journal.pone.0135953 |
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author | Cui, Bo Feng, Lei Pan, Zhenzhong Yu, Manli Zeng, Zhanghua Sun, Changjiao Zhao, Xiang Wang, Yan Cui, Haixin |
author_facet | Cui, Bo Feng, Lei Pan, Zhenzhong Yu, Manli Zeng, Zhanghua Sun, Changjiao Zhao, Xiang Wang, Yan Cui, Haixin |
author_sort | Cui, Bo |
collection | PubMed |
description | Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cyhalothrin, a solid nanodispersion, was successfully developed based on melt-emulsification and high-speed shearing methods. The solid nanodispersion presented excellent advantages over conventional pesticide formulations in such formulation functions as dispersibility, stability and bioavailability. The formulation is free of organic solvents, and the use of surfactant is reduced. Therefore, the application of the solid nanodispersion in crop production will improve efficacy and reduce the occurrence of both pesticide residues in food and environmental pollution from pesticides. |
format | Online Article Text |
id | pubmed-4539193 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-45391932015-08-24 Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin Cui, Bo Feng, Lei Pan, Zhenzhong Yu, Manli Zeng, Zhanghua Sun, Changjiao Zhao, Xiang Wang, Yan Cui, Haixin PLoS One Research Article Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cyhalothrin, a solid nanodispersion, was successfully developed based on melt-emulsification and high-speed shearing methods. The solid nanodispersion presented excellent advantages over conventional pesticide formulations in such formulation functions as dispersibility, stability and bioavailability. The formulation is free of organic solvents, and the use of surfactant is reduced. Therefore, the application of the solid nanodispersion in crop production will improve efficacy and reduce the occurrence of both pesticide residues in food and environmental pollution from pesticides. Public Library of Science 2015-08-17 /pmc/articles/PMC4539193/ /pubmed/26281043 http://dx.doi.org/10.1371/journal.pone.0135953 Text en © 2015 Cui et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. |
spellingShingle | Research Article Cui, Bo Feng, Lei Pan, Zhenzhong Yu, Manli Zeng, Zhanghua Sun, Changjiao Zhao, Xiang Wang, Yan Cui, Haixin Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title | Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title_full | Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title_fullStr | Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title_full_unstemmed | Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title_short | Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin |
title_sort | evaluation of stability and biological activity of solid nanodispersion of lambda-cyhalothrin |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539193/ https://www.ncbi.nlm.nih.gov/pubmed/26281043 http://dx.doi.org/10.1371/journal.pone.0135953 |
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