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Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin

Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cy...

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Autores principales: Cui, Bo, Feng, Lei, Pan, Zhenzhong, Yu, Manli, Zeng, Zhanghua, Sun, Changjiao, Zhao, Xiang, Wang, Yan, Cui, Haixin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539193/
https://www.ncbi.nlm.nih.gov/pubmed/26281043
http://dx.doi.org/10.1371/journal.pone.0135953
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author Cui, Bo
Feng, Lei
Pan, Zhenzhong
Yu, Manli
Zeng, Zhanghua
Sun, Changjiao
Zhao, Xiang
Wang, Yan
Cui, Haixin
author_facet Cui, Bo
Feng, Lei
Pan, Zhenzhong
Yu, Manli
Zeng, Zhanghua
Sun, Changjiao
Zhao, Xiang
Wang, Yan
Cui, Haixin
author_sort Cui, Bo
collection PubMed
description Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cyhalothrin, a solid nanodispersion, was successfully developed based on melt-emulsification and high-speed shearing methods. The solid nanodispersion presented excellent advantages over conventional pesticide formulations in such formulation functions as dispersibility, stability and bioavailability. The formulation is free of organic solvents, and the use of surfactant is reduced. Therefore, the application of the solid nanodispersion in crop production will improve efficacy and reduce the occurrence of both pesticide residues in food and environmental pollution from pesticides.
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spelling pubmed-45391932015-08-24 Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin Cui, Bo Feng, Lei Pan, Zhenzhong Yu, Manli Zeng, Zhanghua Sun, Changjiao Zhao, Xiang Wang, Yan Cui, Haixin PLoS One Research Article Pesticides are essential agrochemicals used to protect plants from diseases, pests and weeds. However, the formulation defects of conventional pesticides cause food toxicity and ecological environmental problems. In this study, a novel, efficient and environmentally friendly formulation of lambda-cyhalothrin, a solid nanodispersion, was successfully developed based on melt-emulsification and high-speed shearing methods. The solid nanodispersion presented excellent advantages over conventional pesticide formulations in such formulation functions as dispersibility, stability and bioavailability. The formulation is free of organic solvents, and the use of surfactant is reduced. Therefore, the application of the solid nanodispersion in crop production will improve efficacy and reduce the occurrence of both pesticide residues in food and environmental pollution from pesticides. Public Library of Science 2015-08-17 /pmc/articles/PMC4539193/ /pubmed/26281043 http://dx.doi.org/10.1371/journal.pone.0135953 Text en © 2015 Cui et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Cui, Bo
Feng, Lei
Pan, Zhenzhong
Yu, Manli
Zeng, Zhanghua
Sun, Changjiao
Zhao, Xiang
Wang, Yan
Cui, Haixin
Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title_full Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title_fullStr Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title_full_unstemmed Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title_short Evaluation of Stability and Biological Activity of Solid Nanodispersion of Lambda-Cyhalothrin
title_sort evaluation of stability and biological activity of solid nanodispersion of lambda-cyhalothrin
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539193/
https://www.ncbi.nlm.nih.gov/pubmed/26281043
http://dx.doi.org/10.1371/journal.pone.0135953
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