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Both RyRs and TPCs are required for NAADP-induced intracellular Ca(2+) release

Intracellular Ca(2+) release is mostly mediated by inositol trisphosphate, but intracellular cyclic-ADP-ribose (cADPR) and nicotinic acid adenine dinucleotide phosphate (NAADP) are important messengers in many systems. Whereas cADPR generally activates type 2 ryanodine receptors (RyR2s), the NAADP-a...

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Detalles Bibliográficos
Autores principales:	Gerasimenko, Julia V., Charlesworth, Richard M., Sherwood, Mark W., Ferdek, Pawel E., Mikoshiba, Katsuhiko, Parrington, John, Petersen, Ole H., Gerasimenko, Oleg V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539342/ https://www.ncbi.nlm.nih.gov/pubmed/26100948 http://dx.doi.org/10.1016/j.ceca.2015.05.005

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