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Endothelial cells induce cancer stem cell features in differentiated glioblastoma cells via bFGF
BACKGROUND: Glioblastoma multiforme (GBM) is a rapidly growing malignant brain tumor, which has been reported to be organized in a hierarchical fashion with cancer stem cells (CSCs) at the apex. Recent studies demonstrate that this hierarchy does not follow a one-way route but can be reverted with m...
Autores principales: | Fessler, Evelyn, Borovski, Tijana, Medema, Jan Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539660/ https://www.ncbi.nlm.nih.gov/pubmed/26282129 http://dx.doi.org/10.1186/s12943-015-0420-3 |
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