Hidden genes in birds

We report that a subset of avian genes is characterized by very high GC content and long G/C stretches. These sequence characteristics correlate with the frequent absence of these genes from genomic databases. We provide several examples where genes in this subset are mistakenly reported as missing...

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Detalles Bibliográficos
Autores principales: Hron, Tomáš, Pajer, Petr, Pačes, Jan, Bartůněk, Petr, Elleder, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539667/
https://www.ncbi.nlm.nih.gov/pubmed/26283656
http://dx.doi.org/10.1186/s13059-015-0724-z
Descripción
Sumario:We report that a subset of avian genes is characterized by very high GC content and long G/C stretches. These sequence characteristics correlate with the frequent absence of these genes from genomic databases. We provide several examples where genes in this subset are mistakenly reported as missing in birds. www.dx.doi.org/10.1186/s13059-015-0725-y ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13059-015-0724-z) contains supplementary material, which is available to authorized users.

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