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Bipartite structure of the inactive mouse X chromosome

BACKGROUND: In mammals, one of the female X chromosomes and all imprinted genes are expressed exclusively from a single allele in somatic cells. To evaluate structural changes associated with allelic silencing, we have applied a recently developed Hi-C assay that uses DNase I for chromatin fragmenta...

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Detalles Bibliográficos
Autores principales: Deng, Xinxian, Ma, Wenxiu, Ramani, Vijay, Hill, Andrew, Yang, Fan, Ay, Ferhat, Berletch, Joel B., Blau, Carl Anthony, Shendure, Jay, Duan, Zhijun, Noble, William S., Disteche, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539712/
https://www.ncbi.nlm.nih.gov/pubmed/26248554
http://dx.doi.org/10.1186/s13059-015-0728-8