Safety and Immunogenicity of a Subvirion Monovalent Unadjuvanted Inactivated Influenza A(H3N2) Variant Vaccine in Healthy Persons ≥18 Years Old

Background. Variant influenza A(H3N2) viruses (H3N2v) have transmitted recently from pigs to humans in the United States. Vaccines strategies are needed. Methods. Healthy adults received 2 doses of subvirion H3N2v vaccine (15 µg of hemagglutinin/dose) 21 days apart in this open-label trial. Serum he...

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Detalles Bibliográficos
Autores principales: Keitel, Wendy A., Jackson, Lisa A., Edupuganti, Srilatha, Winokur, Patricia L., Mulligan, Mark J., Thornburg, Natalie J., Patel, Shital M., Rouphael, Nadine G., Lai, Lilin, Bangaru, Sandhya, McNeal, Monica M., Bellamy, Abbie R., Hill, Heather R., Bond, Nanette, Bosworth, Kathy, Brown, Janet, Banay, Jess, Cheesman, Coni, Lanford, Tracey, Munoz, Flor, Wells, Janet, Carste, Barb, Dunstan, Maya, Mathis, Angel, Parikh, Mihir, Phillips, C. Hallie, Spingola, Alyssa, Starkovich, Pat, Suyehira, Janice, Beck, Allison, Mask, Karen, Bower, Mary, Osinski, Eileen, Rimann, Nayoka, Turner, Pamela, Wang, DongLi, Stapleton, Jack, Won, Regina, Wagner, Nancy, Dull, Geraldine, Gerot, Necole, Reidy, Mary, Zhao, Dan, Segar, Ellen, Slaughter, James C., McDonough, Megan, He, Fenhua, Salata, Robert, Meissner, Cody, Sheffield, Jeanne, Spigarelli, Michael, Greenberg, Stephen, Agrawal, Anoop, Dublin, Sascha, Arterburn, David, Rimland, David, Ribner, Bruce, Meier, Jeff, Buchanan, Wendy, Chang, Soju, Lambert, Linda, Murray, Suzanne, Riddle, Valerie, Spiro, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539893/
https://www.ncbi.nlm.nih.gov/pubmed/25649171
http://dx.doi.org/10.1093/infdis/jiv056

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