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DNA loops generate intracentromere tension in mitosis

The centromere is the DNA locus that dictates kinetochore formation and is visibly apparent as heterochromatin that bridges sister kinetochores in metaphase. Sister centromeres are compacted and held together by cohesin, condensin, and topoisomerase-mediated entanglements until all sister chromosome...

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Detalles Bibliográficos
Autores principales: Lawrimore, Josh, Vasquez, Paula A., Falvo, Michael R., Taylor, Russell M., Vicci, Leandra, Yeh, Elaine, Forest, M. Gregory, Bloom, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539978/
https://www.ncbi.nlm.nih.gov/pubmed/26283798
http://dx.doi.org/10.1083/jcb.201502046