Prion-like domains in RNA binding proteins are essential for building subnuclear paraspeckles

Prion-like domains (PLDs) are low complexity sequences found in RNA binding proteins associated with the neurodegenerative disorder amyotrophic lateral sclerosis. Recently, PLDs have been implicated in mediating gene regulation via liquid-phase transitions that drive ribonucleoprotein granule assemb...

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Detalles Bibliográficos
Autores principales: Hennig, Sven, Kong, Geraldine, Mannen, Taro, Sadowska, Agata, Kobelke, Simon, Blythe, Amanda, Knott, Gavin J., Iyer, K. Swaminathan, Ho, Diwei, Newcombe, Estella A., Hosoki, Kana, Goshima, Naoki, Kawaguchi, Tetsuya, Hatters, Danny, Trinkle-Mulcahy, Laura, Hirose, Tetsuro, Bond, Charles S., Fox, Archa H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539981/
https://www.ncbi.nlm.nih.gov/pubmed/26283796
http://dx.doi.org/10.1083/jcb.201504117

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