α-Catenin–mediated cadherin clustering couples cadherin and actin dynamics

The function of the actin-binding domain of α-catenin, αABD, including its possible role in the direct anchorage of the cadherin–catenin complex to the actin cytoskeleton, has remained uncertain. We identified two point mutations on the αABD surface that interfere with αABD binding to actin and used...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Shuo, Hong, Soonjin, Indra, Indrajyoti, Sergeeva, Alina P., Troyanovsky, Regina B., Shapiro, Lawrence, Honig, Barry, Troyanovsky, Sergey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539995/
https://www.ncbi.nlm.nih.gov/pubmed/26261181
http://dx.doi.org/10.1083/jcb.201412064

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