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Submembrane ATP and Ca(2+) kinetics in α-cells: unexpected signaling for glucagon secretion

Cytoplasmic ATP and Ca(2+) are implicated in current models of glucose’s control of glucagon and insulin secretion from pancreatic α- and β-cells, respectively, but little is known about ATP and its relation to Ca(2+) in α-cells. We therefore expressed the fluorescent ATP biosensor Perceval in mouse...

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Detalles Bibliográficos
Autores principales:	Li, Jia, Yu, Qian, Ahooghalandari, Parvin, Gribble, Fiona M., Reimann, Frank, Tengholm, Anders, Gylfe, Erik
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2015
Materias:	Research Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4539996/ https://www.ncbi.nlm.nih.gov/pubmed/25911612 http://dx.doi.org/10.1096/fj.14-265918

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