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Neuregulin 1 Prevents Phencyclidine-Induced Behavioral Impairments and Disruptions to GABAergic Signaling in Mice
BACKGROUND: Substantial evidence from human post-mortem and genetic studies has linked the neurotrophic factor neuregulin 1 (NRG1) to the pathophysiology of schizophrenia. Genetic animal models and in vitro experiments have suggested that altered NRG1 signaling, rather than protein changes, contribu...
Autores principales: | Engel, Martin, Snikeris, Peta, Jenner, Andrew, Karl, Tim, Huang, Xu-Feng, Frank, Elisabeth |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540095/ https://www.ncbi.nlm.nih.gov/pubmed/26478928 http://dx.doi.org/10.1093/ijnp/pyu114 |
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