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Neuregulin 1 Prevents Phencyclidine-Induced Behavioral Impairments and Disruptions to GABAergic Signaling in Mice

BACKGROUND: Substantial evidence from human post-mortem and genetic studies has linked the neurotrophic factor neuregulin 1 (NRG1) to the pathophysiology of schizophrenia. Genetic animal models and in vitro experiments have suggested that altered NRG1 signaling, rather than protein changes, contribu...

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Detalles Bibliográficos
Autores principales: Engel, Martin, Snikeris, Peta, Jenner, Andrew, Karl, Tim, Huang, Xu-Feng, Frank, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540095/
https://www.ncbi.nlm.nih.gov/pubmed/26478928
http://dx.doi.org/10.1093/ijnp/pyu114

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