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Isolation Housing Exacerbates Alzheimer’s Disease-Like Pathophysiology in Aged APP/PS1 Mice

BACKGROUND: Alzheimer’s disease is a neurodegenerative disease characterized by gradual declines in social, cognitive, and emotional functions, leading to a loss of expected social behavior. Social isolation has been shown to have adverse effects on individual development and growth as well as healt...

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Detalles Bibliográficos
Autores principales: Huang, Huang, Wang, Linmei, Cao, Min, Marshall, Charles, Gao, Junying, Xiao, Na, Hu, Gang, Xiao, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540096/
https://www.ncbi.nlm.nih.gov/pubmed/25568286
http://dx.doi.org/10.1093/ijnp/pyu116