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Parsimonious Determination of the Optimal Infectious Dose of a Pathogen for Nonhuman Primate Models
The nonhuman primate (NHP) model is often the best experimental model for testing interventions designed to block infection by human pathogens, such as HIV, tuberculosis, and malaria. A physiological model may require the use of a limiting dose of the infectious agent, where only a fraction of anima...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540461/ https://www.ncbi.nlm.nih.gov/pubmed/26285041 http://dx.doi.org/10.1371/journal.ppat.1005100 |