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Type 2 segmental glomangioma - Case report

Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was pr...

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Detalles Bibliográficos
Autores principales: Cabral, Camila Raposo, de Oliveira Filho, Jayme, Matsumoto, Julliene Lika, Cignachi, Stela, Tebet, Ana Carolina Franco, Nasser, Kássila da Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540520/
https://www.ncbi.nlm.nih.gov/pubmed/26312686
http://dx.doi.org/10.1590/abd1806-4841.20152483
Descripción
Sumario:Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.