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Type 2 segmental glomangioma - Case report

Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was pr...

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Autores principales: Cabral, Camila Raposo, de Oliveira Filho, Jayme, Matsumoto, Julliene Lika, Cignachi, Stela, Tebet, Ana Carolina Franco, Nasser, Kássila da Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540520/
https://www.ncbi.nlm.nih.gov/pubmed/26312686
http://dx.doi.org/10.1590/abd1806-4841.20152483
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author Cabral, Camila Raposo
de Oliveira Filho, Jayme
Matsumoto, Julliene Lika
Cignachi, Stela
Tebet, Ana Carolina Franco
Nasser, Kássila da Rosa
author_facet Cabral, Camila Raposo
de Oliveira Filho, Jayme
Matsumoto, Julliene Lika
Cignachi, Stela
Tebet, Ana Carolina Franco
Nasser, Kássila da Rosa
author_sort Cabral, Camila Raposo
collection PubMed
description Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative.
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spelling pubmed-45405202015-08-20 Type 2 segmental glomangioma - Case report Cabral, Camila Raposo de Oliveira Filho, Jayme Matsumoto, Julliene Lika Cignachi, Stela Tebet, Ana Carolina Franco Nasser, Kássila da Rosa An Bras Dermatol Case Report Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance. We report a case of a patient with hemangiomatous lesions on the calcaneus and wrist since birth. In 6 years, there was progression of lesions throughout the body. Multiple glomangiomas are asymptomatic and more common in childhood. They can be confused with other vascular malformations. Histopathological diagnosis is essential. The case shows a type 2 segmental manifestation that can be explained by genetic mutation leading to the loss of heterozygosity. As the child grows, the lesions may disseminate due to mutation in distant parts of the skin. Literature shows few reports. The treatment is conservative. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540520/ /pubmed/26312686 http://dx.doi.org/10.1590/abd1806-4841.20152483 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cabral, Camila Raposo
de Oliveira Filho, Jayme
Matsumoto, Julliene Lika
Cignachi, Stela
Tebet, Ana Carolina Franco
Nasser, Kássila da Rosa
Type 2 segmental glomangioma - Case report
title Type 2 segmental glomangioma - Case report
title_full Type 2 segmental glomangioma - Case report
title_fullStr Type 2 segmental glomangioma - Case report
title_full_unstemmed Type 2 segmental glomangioma - Case report
title_short Type 2 segmental glomangioma - Case report
title_sort type 2 segmental glomangioma - case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540520/
https://www.ncbi.nlm.nih.gov/pubmed/26312686
http://dx.doi.org/10.1590/abd1806-4841.20152483
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