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Bullous and hemorrhagic lichen sclerosus - Case report

Lichen sclerosus is a chronic inflammatory disease, usually located in the genital area. The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors. Bullous clinical form stems from hydropic degeneration of the basal membrane, const...

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Autores principales: Lima, Raquel Sucupira Andrade, Maquiné, Gustavo Ávila, Schettini, Antônio Pedro Mendes, Santos, Mônica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540526/
https://www.ncbi.nlm.nih.gov/pubmed/26312692
http://dx.doi.org/10.1590/abd1806-4841.20153502
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author Lima, Raquel Sucupira Andrade
Maquiné, Gustavo Ávila
Schettini, Antônio Pedro Mendes
Santos, Mônica
author_facet Lima, Raquel Sucupira Andrade
Maquiné, Gustavo Ávila
Schettini, Antônio Pedro Mendes
Santos, Mônica
author_sort Lima, Raquel Sucupira Andrade
collection PubMed
description Lichen sclerosus is a chronic inflammatory disease, usually located in the genital area. The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors. Bullous clinical form stems from hydropic degeneration of the basal membrane, constituting a less frequent variant of the disease. In this work, we report the case of a female patient, 55 years old, who in the last three years presented whitish plaques, with horny spikes, located on back and arms. Some of these lesions evolved with hemorrhagic blisters, which after histopathological examination confirmed the diagnosis of bullous and hemorrhagic lichen sclerosus. The patient was treated with high-potency topical corticosteroid for two months, resulting in remission of bullous and hemorrhagic lesions.
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spelling pubmed-45405262015-08-20 Bullous and hemorrhagic lichen sclerosus - Case report Lima, Raquel Sucupira Andrade Maquiné, Gustavo Ávila Schettini, Antônio Pedro Mendes Santos, Mônica An Bras Dermatol Case Report Lichen sclerosus is a chronic inflammatory disease, usually located in the genital area. The etiology of lichen sclerosus is multifactorial, with participation of genetic, autoimmune, infectious and hormonal factors. Bullous clinical form stems from hydropic degeneration of the basal membrane, constituting a less frequent variant of the disease. In this work, we report the case of a female patient, 55 years old, who in the last three years presented whitish plaques, with horny spikes, located on back and arms. Some of these lesions evolved with hemorrhagic blisters, which after histopathological examination confirmed the diagnosis of bullous and hemorrhagic lichen sclerosus. The patient was treated with high-potency topical corticosteroid for two months, resulting in remission of bullous and hemorrhagic lesions. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540526/ /pubmed/26312692 http://dx.doi.org/10.1590/abd1806-4841.20153502 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lima, Raquel Sucupira Andrade
Maquiné, Gustavo Ávila
Schettini, Antônio Pedro Mendes
Santos, Mônica
Bullous and hemorrhagic lichen sclerosus - Case report
title Bullous and hemorrhagic lichen sclerosus - Case report
title_full Bullous and hemorrhagic lichen sclerosus - Case report
title_fullStr Bullous and hemorrhagic lichen sclerosus - Case report
title_full_unstemmed Bullous and hemorrhagic lichen sclerosus - Case report
title_short Bullous and hemorrhagic lichen sclerosus - Case report
title_sort bullous and hemorrhagic lichen sclerosus - case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540526/
https://www.ncbi.nlm.nih.gov/pubmed/26312692
http://dx.doi.org/10.1590/abd1806-4841.20153502
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