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Palmar and plantar lichen planus: a case report and review of the literature
Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Sociedade Brasileira de Dermatologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540542/ https://www.ncbi.nlm.nih.gov/pubmed/26312708 http://dx.doi.org/10.1590/abd1806-4841.20153034 |
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author | Velez, Ana Maria Abreu Howard, Michael S Pereyo, Neville |
author_facet | Velez, Ana Maria Abreu Howard, Michael S Pereyo, Neville |
author_sort | Velez, Ana Maria Abreu |
collection | PubMed |
description | Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Immunohistochemical staining revealed positivity within the epidermis and/or lichenoid infiltrate with CD3, CD8, CD45, CD68, myeloid histiod antigen, BCL2, p27, p53, HLA-DPDQDR, metallothionein and tissue inhibitor of metalloproteinases 1. The diagnosis of PPLP was thus confirmed; this case illustrates that PPLP should be considered in the differential diagnosis of uncommon foot dermatoses with a significant junctional inflammatory component. |
format | Online Article Text |
id | pubmed-4540542 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Sociedade Brasileira de Dermatologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-45405422015-08-20 Palmar and plantar lichen planus: a case report and review of the literature Velez, Ana Maria Abreu Howard, Michael S Pereyo, Neville An Bras Dermatol Case Report Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Immunohistochemical staining revealed positivity within the epidermis and/or lichenoid infiltrate with CD3, CD8, CD45, CD68, myeloid histiod antigen, BCL2, p27, p53, HLA-DPDQDR, metallothionein and tissue inhibitor of metalloproteinases 1. The diagnosis of PPLP was thus confirmed; this case illustrates that PPLP should be considered in the differential diagnosis of uncommon foot dermatoses with a significant junctional inflammatory component. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540542/ /pubmed/26312708 http://dx.doi.org/10.1590/abd1806-4841.20153034 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Velez, Ana Maria Abreu Howard, Michael S Pereyo, Neville Palmar and plantar lichen planus: a case report and review of the literature |
title | Palmar and plantar lichen planus: a case report and review of the
literature |
title_full | Palmar and plantar lichen planus: a case report and review of the
literature |
title_fullStr | Palmar and plantar lichen planus: a case report and review of the
literature |
title_full_unstemmed | Palmar and plantar lichen planus: a case report and review of the
literature |
title_short | Palmar and plantar lichen planus: a case report and review of the
literature |
title_sort | palmar and plantar lichen planus: a case report and review of the
literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540542/ https://www.ncbi.nlm.nih.gov/pubmed/26312708 http://dx.doi.org/10.1590/abd1806-4841.20153034 |
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