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Palmar and plantar lichen planus: a case report and review of the literature

Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated...

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Autores principales: Velez, Ana Maria Abreu, Howard, Michael S, Pereyo, Neville
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540542/
https://www.ncbi.nlm.nih.gov/pubmed/26312708
http://dx.doi.org/10.1590/abd1806-4841.20153034
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author Velez, Ana Maria Abreu
Howard, Michael S
Pereyo, Neville
author_facet Velez, Ana Maria Abreu
Howard, Michael S
Pereyo, Neville
author_sort Velez, Ana Maria Abreu
collection PubMed
description Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Immunohistochemical staining revealed positivity within the epidermis and/or lichenoid infiltrate with CD3, CD8, CD45, CD68, myeloid histiod antigen, BCL2, p27, p53, HLA-DPDQDR, metallothionein and tissue inhibitor of metalloproteinases 1. The diagnosis of PPLP was thus confirmed; this case illustrates that PPLP should be considered in the differential diagnosis of uncommon foot dermatoses with a significant junctional inflammatory component.
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spelling pubmed-45405422015-08-20 Palmar and plantar lichen planus: a case report and review of the literature Velez, Ana Maria Abreu Howard, Michael S Pereyo, Neville An Bras Dermatol Case Report Palmoplantar lichen planus is an uncommon dermatosis. We present a case of 38-year-old Caucasian male with a history of pruritic, scaly lesions on the right plantar foot. Physical examination revealed whitish plaques and numerous spiny hyperkeratotic papules and focal scaling. A biopsy demonstrated orthohyperkeratosis and acanthosis of the epidermis. Immunohistochemical staining revealed positivity within the epidermis and/or lichenoid infiltrate with CD3, CD8, CD45, CD68, myeloid histiod antigen, BCL2, p27, p53, HLA-DPDQDR, metallothionein and tissue inhibitor of metalloproteinases 1. The diagnosis of PPLP was thus confirmed; this case illustrates that PPLP should be considered in the differential diagnosis of uncommon foot dermatoses with a significant junctional inflammatory component. Sociedade Brasileira de Dermatologia 2015 /pmc/articles/PMC4540542/ /pubmed/26312708 http://dx.doi.org/10.1590/abd1806-4841.20153034 Text en © 2015 by Anais Brasileiros de Dermatologia http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Velez, Ana Maria Abreu
Howard, Michael S
Pereyo, Neville
Palmar and plantar lichen planus: a case report and review of the literature
title Palmar and plantar lichen planus: a case report and review of the literature
title_full Palmar and plantar lichen planus: a case report and review of the literature
title_fullStr Palmar and plantar lichen planus: a case report and review of the literature
title_full_unstemmed Palmar and plantar lichen planus: a case report and review of the literature
title_short Palmar and plantar lichen planus: a case report and review of the literature
title_sort palmar and plantar lichen planus: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540542/
https://www.ncbi.nlm.nih.gov/pubmed/26312708
http://dx.doi.org/10.1590/abd1806-4841.20153034
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