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Diversified Control Paths: A Significant Way Disease Genes Perturb the Human Regulatory Network

BACKGROUND: The complexity of biological systems motivates us to use the underlying networks to provide deep understanding of disease etiology and the human diseases are viewed as perturbations of dynamic properties of networks. Control theory that deals with dynamic systems has been successfully us...

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Detalles Bibliográficos
Autores principales: Wang, Bingbo, Gao, Lin, Zhang, Qingfang, Li, Aimin, Deng, Yue, Guo, Xingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540569/
https://www.ncbi.nlm.nih.gov/pubmed/26284649
http://dx.doi.org/10.1371/journal.pone.0135491