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Diversified Control Paths: A Significant Way Disease Genes Perturb the Human Regulatory Network
BACKGROUND: The complexity of biological systems motivates us to use the underlying networks to provide deep understanding of disease etiology and the human diseases are viewed as perturbations of dynamic properties of networks. Control theory that deals with dynamic systems has been successfully us...
Autores principales: | Wang, Bingbo, Gao, Lin, Zhang, Qingfang, Li, Aimin, Deng, Yue, Guo, Xingli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540569/ https://www.ncbi.nlm.nih.gov/pubmed/26284649 http://dx.doi.org/10.1371/journal.pone.0135491 |
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