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α-Spinasterol, a TRPV1 receptor antagonist, elevates the seizure threshold in three acute seizure tests in mice
α-Spinasterol is a plant-derived compound which was reported to act as a selective antagonist for the transient receptor potential vanilloid 1 (TRPV1) receptor. Several studies revealed that the TRPV1 receptors might modulate seizure activity in animal models of seizures and epilepsy. The aim of the...
Autores principales: | Socała, Katarzyna, Nieoczym, Dorota, Pieróg, Mateusz, Wlaź, Piotr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Vienna
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4540766/ https://www.ncbi.nlm.nih.gov/pubmed/25764210 http://dx.doi.org/10.1007/s00702-015-1391-7 |
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