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Sarcopenia Is Associated with High Pulse Pressure in Older Women
Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. M...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541009/ https://www.ncbi.nlm.nih.gov/pubmed/26346157 http://dx.doi.org/10.1155/2015/109824 |
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author | Coelho Júnior, Hélio José Aguiar, Samuel da Silva Gonçalves, Ivan de Oliveira Sampaio, Ricardo Aurélio Carvalho Uchida, Marco Carlos Moraes, Milton Rocha Asano, Ricardo Yukio |
author_facet | Coelho Júnior, Hélio José Aguiar, Samuel da Silva Gonçalves, Ivan de Oliveira Sampaio, Ricardo Aurélio Carvalho Uchida, Marco Carlos Moraes, Milton Rocha Asano, Ricardo Yukio |
author_sort | Coelho Júnior, Hélio José |
collection | PubMed |
description | Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = −226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects. |
format | Online Article Text |
id | pubmed-4541009 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-45410092015-09-06 Sarcopenia Is Associated with High Pulse Pressure in Older Women Coelho Júnior, Hélio José Aguiar, Samuel da Silva Gonçalves, Ivan de Oliveira Sampaio, Ricardo Aurélio Carvalho Uchida, Marco Carlos Moraes, Milton Rocha Asano, Ricardo Yukio J Aging Res Research Article Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = −226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects. Hindawi Publishing Corporation 2015 2015-08-05 /pmc/articles/PMC4541009/ /pubmed/26346157 http://dx.doi.org/10.1155/2015/109824 Text en Copyright © 2015 Hélio José Coelho Júnior et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Coelho Júnior, Hélio José Aguiar, Samuel da Silva Gonçalves, Ivan de Oliveira Sampaio, Ricardo Aurélio Carvalho Uchida, Marco Carlos Moraes, Milton Rocha Asano, Ricardo Yukio Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title_full | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title_fullStr | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title_full_unstemmed | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title_short | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
title_sort | sarcopenia is associated with high pulse pressure in older women |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541009/ https://www.ncbi.nlm.nih.gov/pubmed/26346157 http://dx.doi.org/10.1155/2015/109824 |
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