Cargando…

Sarcopenia Is Associated with High Pulse Pressure in Older Women

Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. M...

Descripción completa

Detalles Bibliográficos
Autores principales: Coelho Júnior, Hélio José, Aguiar, Samuel da Silva, Gonçalves, Ivan de Oliveira, Sampaio, Ricardo Aurélio Carvalho, Uchida, Marco Carlos, Moraes, Milton Rocha, Asano, Ricardo Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541009/
https://www.ncbi.nlm.nih.gov/pubmed/26346157
http://dx.doi.org/10.1155/2015/109824
_version_ 1782386321735548928
author Coelho Júnior, Hélio José
Aguiar, Samuel da Silva
Gonçalves, Ivan de Oliveira
Sampaio, Ricardo Aurélio Carvalho
Uchida, Marco Carlos
Moraes, Milton Rocha
Asano, Ricardo Yukio
author_facet Coelho Júnior, Hélio José
Aguiar, Samuel da Silva
Gonçalves, Ivan de Oliveira
Sampaio, Ricardo Aurélio Carvalho
Uchida, Marco Carlos
Moraes, Milton Rocha
Asano, Ricardo Yukio
author_sort Coelho Júnior, Hélio José
collection PubMed
description Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = −226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects.
format Online
Article
Text
id pubmed-4541009
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-45410092015-09-06 Sarcopenia Is Associated with High Pulse Pressure in Older Women Coelho Júnior, Hélio José Aguiar, Samuel da Silva Gonçalves, Ivan de Oliveira Sampaio, Ricardo Aurélio Carvalho Uchida, Marco Carlos Moraes, Milton Rocha Asano, Ricardo Yukio J Aging Res Research Article Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n = 43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n = 87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P < 0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β = −226, P < 0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P < 0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects. Hindawi Publishing Corporation 2015 2015-08-05 /pmc/articles/PMC4541009/ /pubmed/26346157 http://dx.doi.org/10.1155/2015/109824 Text en Copyright © 2015 Hélio José Coelho Júnior et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Coelho Júnior, Hélio José
Aguiar, Samuel da Silva
Gonçalves, Ivan de Oliveira
Sampaio, Ricardo Aurélio Carvalho
Uchida, Marco Carlos
Moraes, Milton Rocha
Asano, Ricardo Yukio
Sarcopenia Is Associated with High Pulse Pressure in Older Women
title Sarcopenia Is Associated with High Pulse Pressure in Older Women
title_full Sarcopenia Is Associated with High Pulse Pressure in Older Women
title_fullStr Sarcopenia Is Associated with High Pulse Pressure in Older Women
title_full_unstemmed Sarcopenia Is Associated with High Pulse Pressure in Older Women
title_short Sarcopenia Is Associated with High Pulse Pressure in Older Women
title_sort sarcopenia is associated with high pulse pressure in older women
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541009/
https://www.ncbi.nlm.nih.gov/pubmed/26346157
http://dx.doi.org/10.1155/2015/109824
work_keys_str_mv AT coelhojuniorheliojose sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT aguiarsamueldasilva sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT goncalvesivandeoliveira sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT sampaioricardoaureliocarvalho sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT uchidamarcocarlos sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT moraesmiltonrocha sarcopeniaisassociatedwithhighpulsepressureinolderwomen
AT asanoricardoyukio sarcopeniaisassociatedwithhighpulsepressureinolderwomen