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Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?

BACKGROUND: Some patients show favorable changes in the descending aortic false lumen after conventional repair of acute type A dissection, although the incidence of favorable changes has been reported to be low. We aimed to investigate the incidence of positive postoperative changes in the false lu...

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Autores principales: Kim, Sue Hyun, Kim, Jun Sung, Shin, Yoon Cheol, Kim, Dong Jung, Lim, Cheong, Park, Kay-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541060/
https://www.ncbi.nlm.nih.gov/pubmed/26290834
http://dx.doi.org/10.5090/kjtcs.2015.48.4.238
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author Kim, Sue Hyun
Kim, Jun Sung
Shin, Yoon Cheol
Kim, Dong Jung
Lim, Cheong
Park, Kay-Hyun
author_facet Kim, Sue Hyun
Kim, Jun Sung
Shin, Yoon Cheol
Kim, Dong Jung
Lim, Cheong
Park, Kay-Hyun
author_sort Kim, Sue Hyun
collection PubMed
description BACKGROUND: Some patients show favorable changes in the descending aortic false lumen after conventional repair of acute type A dissection, although the incidence of favorable changes has been reported to be low. We aimed to investigate the incidence of positive postoperative changes in the false lumen and the factors associated with positive outcomes. METHODS: In 63 patients who underwent surgery for type A acute dissection as well as serial computed tomography (CT) scanning, morphological parameters were compared between the preoperative, early postoperative (mean interval, 5.4 days), and late CT scans (mean interval, 31.0 months) at three levels of the descending thoracic aorta. RESULTS: In the early postoperative CT images, complete false lumen thrombosis and/or true lumen expansion at the proximal descending aorta was observed in 46% of the patients. In the late images, complete thrombosis or resolution of the proximal descending false lumen occurred in 42.9% of the patients. Multivariate analysis found that juxta-anastomotic false lumen thrombosis was predictive of favorable early changes, which were in turn predictive of continuing later improvement. CONCLUSION: Even after conventional repair without inserting a frozen elephant trunk, the proximal descending aortic false lumen showed positive remodeling in a substantial number of patients. We believe that the long-term prognosis of type A dissection can be improved by refining surgical technique, and particularly by avoiding large intimal tears at the anastomosis site during the initial repair.
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spelling pubmed-45410602015-08-19 Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable? Kim, Sue Hyun Kim, Jun Sung Shin, Yoon Cheol Kim, Dong Jung Lim, Cheong Park, Kay-Hyun Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: Some patients show favorable changes in the descending aortic false lumen after conventional repair of acute type A dissection, although the incidence of favorable changes has been reported to be low. We aimed to investigate the incidence of positive postoperative changes in the false lumen and the factors associated with positive outcomes. METHODS: In 63 patients who underwent surgery for type A acute dissection as well as serial computed tomography (CT) scanning, morphological parameters were compared between the preoperative, early postoperative (mean interval, 5.4 days), and late CT scans (mean interval, 31.0 months) at three levels of the descending thoracic aorta. RESULTS: In the early postoperative CT images, complete false lumen thrombosis and/or true lumen expansion at the proximal descending aorta was observed in 46% of the patients. In the late images, complete thrombosis or resolution of the proximal descending false lumen occurred in 42.9% of the patients. Multivariate analysis found that juxta-anastomotic false lumen thrombosis was predictive of favorable early changes, which were in turn predictive of continuing later improvement. CONCLUSION: Even after conventional repair without inserting a frozen elephant trunk, the proximal descending aortic false lumen showed positive remodeling in a substantial number of patients. We believe that the long-term prognosis of type A dissection can be improved by refining surgical technique, and particularly by avoiding large intimal tears at the anastomosis site during the initial repair. The Korean Society for Thoracic and Cardiovascular Surgery 2015-08 2015-08-05 /pmc/articles/PMC4541060/ /pubmed/26290834 http://dx.doi.org/10.5090/kjtcs.2015.48.4.238 Text en Copyright © 2015 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Kim, Sue Hyun
Kim, Jun Sung
Shin, Yoon Cheol
Kim, Dong Jung
Lim, Cheong
Park, Kay-Hyun
Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title_full Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title_fullStr Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title_full_unstemmed Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title_short Change of Proximal Descending Aortic False Lumen after Conventional Repair of Acute Type I Dissection: Is It Always Unfavorable?
title_sort change of proximal descending aortic false lumen after conventional repair of acute type i dissection: is it always unfavorable?
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541060/
https://www.ncbi.nlm.nih.gov/pubmed/26290834
http://dx.doi.org/10.5090/kjtcs.2015.48.4.238
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