Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity

Atherosclerotic plaque formation is associated with irregular distribution of wall shear stress (WSS) that modulates endothelial function and integrity. Polycystins (PC)-1/-2 constitute a flow-sensing protein complex in endothelial cells, able to respond to WSS and induce cell-proliferation changes...

Descripción completa

Detalles Bibliográficos
Autores principales: Varela, Aimilia, Piperi, Christina, Sigala, Fragiska, Agrogiannis, George, Davos, Constantinos H., Andri, Maria-Anastasia, Manopoulos, Christos, Tsangaris, Sokrates, Basdra, Efthimia K., Papavassiliou, Athanasios G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541068/
https://www.ncbi.nlm.nih.gov/pubmed/26286632
http://dx.doi.org/10.1038/srep13461

Ejemplares similares

Ejemplares similares