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A Branching Process to Characterize the Dynamics of Stem Cell Differentiation
The understanding of the regulatory processes that orchestrate stem cell maintenance is a cornerstone in developmental biology. Here, we present a mathematical model based on a branching process formalism that predicts average rates of proliferative and differentiative divisions in a given stem cell...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541069/ https://www.ncbi.nlm.nih.gov/pubmed/26286123 http://dx.doi.org/10.1038/srep13265 |