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A Branching Process to Characterize the Dynamics of Stem Cell Differentiation

The understanding of the regulatory processes that orchestrate stem cell maintenance is a cornerstone in developmental biology. Here, we present a mathematical model based on a branching process formalism that predicts average rates of proliferative and differentiative divisions in a given stem cell...

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Detalles Bibliográficos
Autor principal: Míguez, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541069/
https://www.ncbi.nlm.nih.gov/pubmed/26286123
http://dx.doi.org/10.1038/srep13265