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Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method
BACKGROUND AND AIMS: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon's...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541177/ https://www.ncbi.nlm.nih.gov/pubmed/26330709 http://dx.doi.org/10.4103/0970-9185.161666 |
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author | Ashay, Nerurkar Aparna Wasim, Shaikh Anil, Tendolkar Bharati |
author_facet | Ashay, Nerurkar Aparna Wasim, Shaikh Anil, Tendolkar Bharati |
author_sort | Ashay, Nerurkar Aparna |
collection | PubMed |
description | BACKGROUND AND AIMS: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon's up-and-down method. MATERIAL AND METHODS: Prospective randomized controlled trial (n-60) was planned. I-gel or cLMA was inserted 60 s after propofol injection whose dose was calculated based on previous patients response as per Dixon's up-and-down method. Propofol requirements for successful placement of devices was noted and compared. Difference between the groups was measured by ANOVA. A P < 0.05 was considered as statistically significant. RESULTS: Significantly lower (P < 0.001) propofol dose was required for I-gel (2.02 ± 0.26 mg/kg) insertion than cLMA (2.70 ± 0.28 mg/kg). CONCLUSIONS: I-gel requires significantly lower dose of propofol for insertion when compared to cLMA. |
format | Online Article Text |
id | pubmed-4541177 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-45411772015-09-01 Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method Ashay, Nerurkar Aparna Wasim, Shaikh Anil, Tendolkar Bharati J Anaesthesiol Clin Pharmacol Original Article BACKGROUND AND AIMS: Propofol is the drug of choice when used as sole anesthetic agent for placement of supraglottic airway devices. We aimed to find and compare the propofol dose required for smooth first attempt insertion of I-gel versus the classic laryngeal mask airway (cLMA) using Dixon's up-and-down method. MATERIAL AND METHODS: Prospective randomized controlled trial (n-60) was planned. I-gel or cLMA was inserted 60 s after propofol injection whose dose was calculated based on previous patients response as per Dixon's up-and-down method. Propofol requirements for successful placement of devices was noted and compared. Difference between the groups was measured by ANOVA. A P < 0.05 was considered as statistically significant. RESULTS: Significantly lower (P < 0.001) propofol dose was required for I-gel (2.02 ± 0.26 mg/kg) insertion than cLMA (2.70 ± 0.28 mg/kg). CONCLUSIONS: I-gel requires significantly lower dose of propofol for insertion when compared to cLMA. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4541177/ /pubmed/26330709 http://dx.doi.org/10.4103/0970-9185.161666 Text en Copyright: © Journal of Anaesthesiology Clinical Pharmacology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Ashay, Nerurkar Aparna Wasim, Shaikh Anil, Tendolkar Bharati Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title | Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title_full | Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title_fullStr | Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title_full_unstemmed | Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title_short | Propofol requirement for insertion of I-gel versus laryngeal mask airway: A comparative dose finding study using Dixon's up-and-down method |
title_sort | propofol requirement for insertion of i-gel versus laryngeal mask airway: a comparative dose finding study using dixon's up-and-down method |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541177/ https://www.ncbi.nlm.nih.gov/pubmed/26330709 http://dx.doi.org/10.4103/0970-9185.161666 |
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