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Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology
This study was aimed to optimize the extraction process for Salvia miltiorrhiza Bunge polysaccharide using response surface methodology The results showed that four operating parameters including microwave power, microwave time and the particle size had notable effects on the polysaccharide extracti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bentham Open
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541331/ https://www.ncbi.nlm.nih.gov/pubmed/26312073 http://dx.doi.org/10.2174/1874120701408010153 |
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author | Yanhua, Wang Fuhua, Wu Zhaohan, Guo Mingxing, Peng Yanan, Zhang Ling, Pang Zhen Minhua, Du Caiying, Zhang Zian, Liang |
author_facet | Yanhua, Wang Fuhua, Wu Zhaohan, Guo Mingxing, Peng Yanan, Zhang Ling, Pang Zhen Minhua, Du Caiying, Zhang Zian, Liang |
author_sort | Yanhua, Wang |
collection | PubMed |
description | This study was aimed to optimize the extraction process for Salvia miltiorrhiza Bunge polysaccharide using response surface methodology The results showed that four operating parameters including microwave power, microwave time and the particle size had notable effects on the polysaccharide extraction of Salvia miltiorrhiza Bunge. The effects could be ranked in decreasing order of importance as follows:. Microwave power > microwave time > the comminution degree. The optimal extraction parameters were determined as 573.83W of Microwave power and 8.4min of microwave time and 67.51mesh of the comminution degree, resulting in the yield of Salvia miltiorrhiza Bunge polysaccharide of 101.161mg / g. The established regression model describing polysaccharide extraction from as a function of the three extraction parameters was highly significant (R 2 = 0.9953). The predicted and experimental results were found to be in good agreement. Thus, the model can be applicable for the prediction of polysaccharide extraction from Salvia miltiorrhiza Bunge. |
format | Online Article Text |
id | pubmed-4541331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Bentham Open |
record_format | MEDLINE/PubMed |
spelling | pubmed-45413312015-08-26 Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology Yanhua, Wang Fuhua, Wu Zhaohan, Guo Mingxing, Peng Yanan, Zhang Ling, Pang Zhen Minhua, Du Caiying, Zhang Zian, Liang Open Biomed Eng J Article This study was aimed to optimize the extraction process for Salvia miltiorrhiza Bunge polysaccharide using response surface methodology The results showed that four operating parameters including microwave power, microwave time and the particle size had notable effects on the polysaccharide extraction of Salvia miltiorrhiza Bunge. The effects could be ranked in decreasing order of importance as follows:. Microwave power > microwave time > the comminution degree. The optimal extraction parameters were determined as 573.83W of Microwave power and 8.4min of microwave time and 67.51mesh of the comminution degree, resulting in the yield of Salvia miltiorrhiza Bunge polysaccharide of 101.161mg / g. The established regression model describing polysaccharide extraction from as a function of the three extraction parameters was highly significant (R 2 = 0.9953). The predicted and experimental results were found to be in good agreement. Thus, the model can be applicable for the prediction of polysaccharide extraction from Salvia miltiorrhiza Bunge. Bentham Open 2014-12-31 /pmc/articles/PMC4541331/ /pubmed/26312073 http://dx.doi.org/10.2174/1874120701408010153 Text en © Yanhua et al; Licensee Bentham Open. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article licensed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited. |
spellingShingle | Article Yanhua, Wang Fuhua, Wu Zhaohan, Guo Mingxing, Peng Yanan, Zhang Ling, Pang Zhen Minhua, Du Caiying, Zhang Zian, Liang Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title | Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title_full | Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title_fullStr | Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title_full_unstemmed | Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title_short | Optimization of Extraction Process for Polysaccharide in Salvia Miltiorrhiza Bunge Using Response Surface Methodology |
title_sort | optimization of extraction process for polysaccharide in salvia miltiorrhiza bunge using response surface methodology |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541331/ https://www.ncbi.nlm.nih.gov/pubmed/26312073 http://dx.doi.org/10.2174/1874120701408010153 |
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