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Extracorporeal liver assist device to exchange albumin and remove endotoxin in acute liver failure: Results of a pivotal pre-clinical study
BACKGROUND & AIMS: In acute liver failure, severity of liver injury and clinical progression of disease are in part consequent upon activation of the innate immune system. Endotoxaemia contributes to innate immune system activation and the detoxifying function of albumin, critical to recovery fr...
Autores principales: | Lee, Karla C.L., Baker, Luisa A., Stanzani, Giacomo, Alibhai, Hatim, Chang, Yu Mei, Jimenez Palacios, Carolina, Leckie, Pamela J., Giordano, Paola, Priestnall, Simon L., Antoine, Daniel J., Jenkins, Rosalind E., Goldring, Christopher E., Park, B. Kevin, Andreola, Fausto, Agarwal, Banwari, Mookerjee, Rajeshwar P., Davies, Nathan A., Jalan, Rajiv |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541472/ https://www.ncbi.nlm.nih.gov/pubmed/25937432 http://dx.doi.org/10.1016/j.jhep.2015.04.020 |
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