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Lipid-mediated regulation of SKN-1/Nrf in response to germ cell absence

In Caenorhabditis elegans, ablation of germline stem cells (GSCs) extends lifespan, but also increases fat accumulation and alters lipid metabolism, raising the intriguing question of how these effects might be related. Here, we show that a lack of GSCs results in a broad transcriptional reprogrammi...

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Detalles Bibliográficos
Autores principales:	Steinbaugh, Michael J, Narasimhan, Sri Devi, Robida-Stubbs, Stacey, Moronetti Mazzeo, Lorenza E, Dreyfuss, Jonathan M, Hourihan, John M, Raghavan, Prashant, Operaña, Theresa N, Esmaillie, Reza, Blackwell, T Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541496/ https://www.ncbi.nlm.nih.gov/pubmed/26196144 http://dx.doi.org/10.7554/eLife.07836

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