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Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up

BACKGROUND: Mometasone furoate-releasing implants have been approved for use in the ethmoid sinuses following endoscopic sinus surgery (ESS) to reduce the need for medical and surgical intervention postoperatively. Outcomes have not yet been studied when these implants are utilized in other paranasa...

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Autor principal: Matheny, Keith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OceanSide Publications, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541632/
https://www.ncbi.nlm.nih.gov/pubmed/26302732
http://dx.doi.org/10.2500/ar.2015.6.0117
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author Matheny, Keith E.
author_facet Matheny, Keith E.
author_sort Matheny, Keith E.
collection PubMed
description BACKGROUND: Mometasone furoate-releasing implants have been approved for use in the ethmoid sinuses following endoscopic sinus surgery (ESS) to reduce the need for medical and surgical intervention postoperatively. Outcomes have not yet been studied when these implants are utilized in other paranasal sinuses after ESS. OBJECTIVE: To present a case in which bioabsorbable steroid-eluting implants were used to maintain patency and to decrease inflammation in the frontal and maxillary sinuses after revision ESS. METHODS: 52-year-old male with lifelong allergic rhinitis, chronic allergic fungal rhinosinusitis, and inflammatory bowel disease had previously undergone four endoscopic sinus surgeries, subcutaneous injection immunotherapy, and topical therapy with budesonide and amphotericin sinus irrigations. In July, 2012, during revision left frontal sinusotomy and right maxillary antrostomy (the fifth ESS), two bioabsorbable steroid-releasing implants were placed in the left frontal recess and the right maxillary sinus respectively and followed clinically, endoscopically, and radiographically for two years. RESULTS: Two year followup demonstrated near complete clinical, endoscopic, and radiographic resolution of the patient's signs and symptoms of chronic rhinosinusitis. CONCLUSIONS: The steroid-releasing implants during the critical phase of wound-healing appear to have allowed the patient, now over two years postoperatively, to achieve a healthier state and to allow more successful management than the preceding 15–20 years.
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spelling pubmed-45416322015-08-24 Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up Matheny, Keith E. Allergy Rhinol (Providence) Articles BACKGROUND: Mometasone furoate-releasing implants have been approved for use in the ethmoid sinuses following endoscopic sinus surgery (ESS) to reduce the need for medical and surgical intervention postoperatively. Outcomes have not yet been studied when these implants are utilized in other paranasal sinuses after ESS. OBJECTIVE: To present a case in which bioabsorbable steroid-eluting implants were used to maintain patency and to decrease inflammation in the frontal and maxillary sinuses after revision ESS. METHODS: 52-year-old male with lifelong allergic rhinitis, chronic allergic fungal rhinosinusitis, and inflammatory bowel disease had previously undergone four endoscopic sinus surgeries, subcutaneous injection immunotherapy, and topical therapy with budesonide and amphotericin sinus irrigations. In July, 2012, during revision left frontal sinusotomy and right maxillary antrostomy (the fifth ESS), two bioabsorbable steroid-releasing implants were placed in the left frontal recess and the right maxillary sinus respectively and followed clinically, endoscopically, and radiographically for two years. RESULTS: Two year followup demonstrated near complete clinical, endoscopic, and radiographic resolution of the patient's signs and symptoms of chronic rhinosinusitis. CONCLUSIONS: The steroid-releasing implants during the critical phase of wound-healing appear to have allowed the patient, now over two years postoperatively, to achieve a healthier state and to allow more successful management than the preceding 15–20 years. OceanSide Publications, Inc. 2015 /pmc/articles/PMC4541632/ /pubmed/26302732 http://dx.doi.org/10.2500/ar.2015.6.0117 Text en Copyright © 2015, OceanSide Publications, Inc., U.S.A. This publication is provided under the terms of the Creative Commons Public License ("CCPL" or "License"), in attribution 3.0 unported (Attribution Non-Commercial No Derivatives (CC BY-NC-ND)), further described at: http://creativecommons.org/licenses/by-nc-nd/3.0/legalcode. The work is protected by copyright and/or other applicable law. Any use of the work other then as authorized under this license or copyright law is prohibited.
spellingShingle Articles
Matheny, Keith E.
Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title_full Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title_fullStr Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title_full_unstemmed Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title_short Bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
title_sort bioabsorbable steroid-releasing sinus implants in the frontal and maxillary sinuses: 2-year follow-up
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541632/
https://www.ncbi.nlm.nih.gov/pubmed/26302732
http://dx.doi.org/10.2500/ar.2015.6.0117
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