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Use of sirolimus in the treatment of lymphangioleiomyomatosis: favorable responses in patients with different extrapulmonary manifestations
OBJECTIVE: Lymphangioleiomyomatosis (LAM) is a rare disease that is currently considered a low-grade neoplasm with metastatic potential and variable progression. Mammalian target of rapamycin (mTOR) inhibitors, such as sirolimus and everolimus, have recently become a treatment option for LAM patient...
Autores principales: | Freitas, Carolina Salim Gonçalves, Baldi, Bruno Guedes, Araújo, Mariana Sponholz, Heiden, Glaucia Itamaro, Kairalla, Ronaldo Adib, Carvalho, Carlos Roberto Ribeiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Pneumologia e Tisiologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541764/ https://www.ncbi.nlm.nih.gov/pubmed/26176526 http://dx.doi.org/10.1590/S1806-37132015000004553 |
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