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Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?

OBJECTIVE: To compare the results of the root reconstruction with the aortic valve-sparing operation versus composite graftvalve replacement. METHODS: From January 2002 to October 2013, 324 patients underwent aortic root reconstruction. They were 263 composite graft-valve replacement and 61 aortic v...

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Autores principales: Lamana, Fernando de Azevedo, Dias, Ricardo Ribeiro, Duncan, Jose Augusto, de Faria, Leandro Batisti, Malbouisson, Luiz Marcelo Sa, Borges, Luciano de Figueiredo, Mady, Charles, Jatene, Fábio Biscegli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cirurgia Cardiovascular 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541781/
https://www.ncbi.nlm.nih.gov/pubmed/26313725
http://dx.doi.org/10.5935/1678-9741.20150028
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author Lamana, Fernando de Azevedo
Dias, Ricardo Ribeiro
Duncan, Jose Augusto
de Faria, Leandro Batisti
Malbouisson, Luiz Marcelo Sa
Borges, Luciano de Figueiredo
Mady, Charles
Jatene, Fábio Biscegli
author_facet Lamana, Fernando de Azevedo
Dias, Ricardo Ribeiro
Duncan, Jose Augusto
de Faria, Leandro Batisti
Malbouisson, Luiz Marcelo Sa
Borges, Luciano de Figueiredo
Mady, Charles
Jatene, Fábio Biscegli
author_sort Lamana, Fernando de Azevedo
collection PubMed
description OBJECTIVE: To compare the results of the root reconstruction with the aortic valve-sparing operation versus composite graftvalve replacement. METHODS: From January 2002 to October 2013, 324 patients underwent aortic root reconstruction. They were 263 composite graft-valve replacement and 61 aortic valve-sparing operation (43 reimplantation and 18 remodeling). Twenty-six percent of the patients were NYHA functional class III and IV; 9.6% had Marfan syndrome, and 12% had bicuspid aortic valve. There was a predominance of aneurysms over dissections (81% vs. 19%), with 7% being acute dissections. The complete follow-up of 100% of the patients was performed with median follow-up time of 902 days for patients undergoing composite graft-valve replacement and 1492 for those undergoing aortic valve-sparing operation. RESULTS: In-hospital mortality was 6.7% and 4.9%, respectively for composite graft-valve replacement and aortic valve-sparing operation (ns). During the late follow-up period, there was 0% moderate and 15.4% severe aortic regurgitation, and NYHA functional class I and II were 89.4% and 94%, respectively for composite graft-valve replacement and aortic valve-sparing operation (ns). Root reconstruction with aortic valve-sparing operation showed lower late mortality (P=0.001) and lower bleeding complications (P=0.006). There was no difference for thromboembolism, endocarditis, and need of reoperation. CONCLUSION: The aortic root reconstruction with preservation of the valve should be the operation being performed for presenting lower late mortality and survival free of bleeding events.
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spelling pubmed-45417812015-08-20 Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients? Lamana, Fernando de Azevedo Dias, Ricardo Ribeiro Duncan, Jose Augusto de Faria, Leandro Batisti Malbouisson, Luiz Marcelo Sa Borges, Luciano de Figueiredo Mady, Charles Jatene, Fábio Biscegli Rev Bras Cir Cardiovasc Original Article OBJECTIVE: To compare the results of the root reconstruction with the aortic valve-sparing operation versus composite graftvalve replacement. METHODS: From January 2002 to October 2013, 324 patients underwent aortic root reconstruction. They were 263 composite graft-valve replacement and 61 aortic valve-sparing operation (43 reimplantation and 18 remodeling). Twenty-six percent of the patients were NYHA functional class III and IV; 9.6% had Marfan syndrome, and 12% had bicuspid aortic valve. There was a predominance of aneurysms over dissections (81% vs. 19%), with 7% being acute dissections. The complete follow-up of 100% of the patients was performed with median follow-up time of 902 days for patients undergoing composite graft-valve replacement and 1492 for those undergoing aortic valve-sparing operation. RESULTS: In-hospital mortality was 6.7% and 4.9%, respectively for composite graft-valve replacement and aortic valve-sparing operation (ns). During the late follow-up period, there was 0% moderate and 15.4% severe aortic regurgitation, and NYHA functional class I and II were 89.4% and 94%, respectively for composite graft-valve replacement and aortic valve-sparing operation (ns). Root reconstruction with aortic valve-sparing operation showed lower late mortality (P=0.001) and lower bleeding complications (P=0.006). There was no difference for thromboembolism, endocarditis, and need of reoperation. CONCLUSION: The aortic root reconstruction with preservation of the valve should be the operation being performed for presenting lower late mortality and survival free of bleeding events. Sociedade Brasileira de Cirurgia Cardiovascular 2015 /pmc/articles/PMC4541781/ /pubmed/26313725 http://dx.doi.org/10.5935/1678-9741.20150028 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lamana, Fernando de Azevedo
Dias, Ricardo Ribeiro
Duncan, Jose Augusto
de Faria, Leandro Batisti
Malbouisson, Luiz Marcelo Sa
Borges, Luciano de Figueiredo
Mady, Charles
Jatene, Fábio Biscegli
Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title_full Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title_fullStr Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title_full_unstemmed Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title_short Surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
title_sort surgery of the aortic root: should we go for the valve-sparing root reconstruction or the composite graft-valve replacement is still the first choice of treatment for these patients?
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541781/
https://www.ncbi.nlm.nih.gov/pubmed/26313725
http://dx.doi.org/10.5935/1678-9741.20150028
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