Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing

Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities re...

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Detalles Bibliográficos
Autores principales: Ku, Ti-Hsuan, Zhang, Tiantian, Luo, Hua, Yen, Tony M., Chen, Ping-Wei, Han, Yuanyuan, Lo, Yu-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541879/
https://www.ncbi.nlm.nih.gov/pubmed/26153774
http://dx.doi.org/10.3390/s150716281
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author Ku, Ti-Hsuan
Zhang, Tiantian
Luo, Hua
Yen, Tony M.
Chen, Ping-Wei
Han, Yuanyuan
Lo, Yu-Hwa
author_facet Ku, Ti-Hsuan
Zhang, Tiantian
Luo, Hua
Yen, Tony M.
Chen, Ping-Wei
Han, Yuanyuan
Lo, Yu-Hwa
author_sort Ku, Ti-Hsuan
collection PubMed
description Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities related to nucleic acid-based aptamer techniques that have been reported in the past two decades. Limitations of aptamers and possible approaches to overcome these limitations are also discussed.
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spelling pubmed-45418792015-08-26 Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing Ku, Ti-Hsuan Zhang, Tiantian Luo, Hua Yen, Tony M. Chen, Ping-Wei Han, Yuanyuan Lo, Yu-Hwa Sensors (Basel) Review Detection of small molecules or proteins of living cells provides an exceptional opportunity to study genetic variations and functions, cellular behaviors, and various diseases including cancer and microbial infections. Our aim in this review is to give an overview of selected research activities related to nucleic acid-based aptamer techniques that have been reported in the past two decades. Limitations of aptamers and possible approaches to overcome these limitations are also discussed. MDPI 2015-07-06 /pmc/articles/PMC4541879/ /pubmed/26153774 http://dx.doi.org/10.3390/s150716281 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ku, Ti-Hsuan
Zhang, Tiantian
Luo, Hua
Yen, Tony M.
Chen, Ping-Wei
Han, Yuanyuan
Lo, Yu-Hwa
Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title_full Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title_fullStr Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title_full_unstemmed Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title_short Nucleic Acid Aptamers: An Emerging Tool for Biotechnology and Biomedical Sensing
title_sort nucleic acid aptamers: an emerging tool for biotechnology and biomedical sensing
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541879/
https://www.ncbi.nlm.nih.gov/pubmed/26153774
http://dx.doi.org/10.3390/s150716281
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