Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases

Vancomycin resistance in Gram-positive bacteria results from the replacement of the d-alanyl–d-alanine target of peptidoglycan precursors with d-alanyl–d-lactate or d-alanyl–d-serine (d-Ala-d-Ser), to which vancomycin has low binding affinity. VanT is one of the proteins required for the production...

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Detalles Bibliográficos
Autores principales: Meziane-Cherif, Djalal, Stogios, Peter J., Evdokimova, Elena, Egorova, Olga, Savchenko, Alexei, Courvalin, Patrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542195/
https://www.ncbi.nlm.nih.gov/pubmed/26265719
http://dx.doi.org/10.1128/mBio.00806-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542195/
https://www.ncbi.nlm.nih.gov/pubmed/26265719
http://dx.doi.org/10.1128/mBio.00806-15

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