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Silibinin down-regulates FAT10 and modulate TNF-α/IFN-γ-induced chromosomal instability and apoptosis sensitivity

Pleiotropic pro-inflammatory cytokines, TNF-α and IFN-γ (TI), play important yet diverse roles in cell survival, proliferation, and death. Recent evidence highlights FAT10 as a downstream molecule in the pathway of inflammation-induced tumorigenesis through mediating the effect of cytokines in causi...

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Detalles Bibliográficos
Autores principales:	Gao, Yun, Theng, Steven Setiawan, Mah, Way-Champ, Lee, Caroline G. L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542280/ https://www.ncbi.nlm.nih.gov/pubmed/26142316 http://dx.doi.org/10.1242/bio.011189

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