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Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation
RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated pre-let-7 uridylation, inhibiting its process...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542301/ https://www.ncbi.nlm.nih.gov/pubmed/25457611 http://dx.doi.org/10.1016/j.celrep.2014.10.017 |