Cargando…

Global Reorganization of the Nuclear Landscape in Senescent Cells

Cellular senescence has been implicated in tumor suppression, development, and aging and is accompanied by large-scale chromatin rearrangements, forming senescence-associated heterochromatic foci (SAHF). However, how the chromatin is reorganized during SAHF formation is poorly understood. Furthermor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chandra, Tamir, Ewels, Philip Andrew, Schoenfelder, Stefan, Furlan-Magaril, Mayra, Wingett, Steven William, Kirschner, Kristina, Thuret, Jean-Yves, Andrews, Simon, Fraser, Peter, Reik, Wolf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542308/ https://www.ncbi.nlm.nih.gov/pubmed/25640177 http://dx.doi.org/10.1016/j.celrep.2014.12.055

Ejemplares similares

HiCUP: pipeline for mapping and processing Hi-C data
por: Wingett, Steven, et al.
Publicado: (2015)

Promoter Capture Hi-C: High-resolution, Genome-wide Profiling of Promoter Interactions
por: Schoenfelder, Stefan, et al.
Publicado: (2018)

Long-Range Enhancer Interactions Are Prevalent in Mouse Embryonic Stem Cells and Are Reorganized upon Pluripotent State Transition
por: Novo, Clara Lopes, et al.
Publicado: (2018)

Global reorganisation of cis-regulatory units upon lineage commitment of human embryonic stem cells
por: Freire-Pritchett, Paula, et al.
Publicado: (2017)

Induction and transmission of oncogene-induced senescence
por: Rattanavirotkul, Nattaphong, et al.
Publicado: (2020)

Polymer Modeling Predicts Chromosome Reorganization in Senescence
por: Chiang, Michael, et al.
Publicado: (2019)

Functional heterogeneity in senescence
por: Kirschner, Kristina, et al.
Publicado: (2020)

The functional impact of nuclear reorganization in cellular senescence
por: Rocha, Azucena, et al.
Publicado: (2021)

The global and promoter-centric 3D genome organization temporally resolved during a circadian cycle
por: Furlan-Magaril, Mayra, et al.
Publicado: (2021)

Nuclear pore density controls heterochromatin reorganization during senescence
por: Boumendil, Charlene, et al.
Publicado: (2019)

Heterochromatin as an Important Driver of Genome Organization
por: Penagos-Puig, Andrés, et al.
Publicado: (2020)

Chromosome conformation capture technologies as tools to detect structural variations and their repercussion in chromatin 3D configuration
por: Stephenson-Gussinye, Aura, et al.
Publicado: (2023)

Editorial: Chromatin Spatial Configuration and Function in Metazoans
por: Delgado-Olguín, Paul, et al.
Publicado: (2021)

RNA proximity sequencing data and analysis pipeline from a human neuroblastoma nuclear transcriptome
por: Wingett, Steven W., et al.
Publicado: (2020)

SC3 - consensus clustering of single-cell RNA-Seq data
por: Kiselev, Vladimir Yu., et al.
Publicado: (2017)

The pluripotent regulatory circuitry connecting promoters to their long-range interacting elements
por: Schoenfelder, Stefan, et al.
Publicado: (2015)

Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites
por: Hänzelmann, Sonja, et al.
Publicado: (2015)

Reorganization of chromosome architecture in replicative cellular senescence
por: Criscione, Steven W., et al.
Publicado: (2016)

Targeting proteostasis maintenance and autophagy in senescence
por: L’Hôte, Valentin, et al.
Publicado: (2022)

Comparison of Hi-C results using in-solution versus in-nucleus ligation
por: Nagano, Takashi, et al.
Publicado: (2015)

Reorganization of the nuclear lamina and cytoskeleton in adipogenesis
por: Verstraeten, Valerie L. R. M., et al.
Publicado: (2011)

From the divergence of senescent cell fates to mechanisms and selectivity of senolytic drugs
por: L'Hôte, Valentin, et al.
Publicado: (2022)

Notch Signaling Mediates Secondary Senescence
por: Teo, Yee Voan, et al.
Publicado: (2019)

Experimental design for single-cell RNA sequencing
por: Baran-Gale, Jeanette, et al.
Publicado: (2017)

Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation
por: Mohammed, Hisham, et al.
Publicado: (2017)

Modelling the dynamics of senescence spread
por: Martin, Lucy, et al.
Publicado: (2023)

Hi-C as a tool for precise detection and characterisation of chromosomal rearrangements and copy number variation in human tumours
por: Harewood, Louise, et al.
Publicado: (2017)

In situ dissection of domain boundaries affect genome topology and gene transcription in Drosophila
por: Arzate-Mejía, Rodrigo G., et al.
Publicado: (2020)

Role of the Nuclear Lamina in Age-Associated Nuclear Reorganization and Inflammation
por: Kristiani, Lidya, et al.
Publicado: (2020)

Involvement of condensin in cellular senescence through gene regulation and compartmental reorganization
por: Iwasaki, Osamu, et al.
Publicado: (2019)

Deacetylation of H4-K16Ac and heterochromatin assembly in senescence
por: Contrepois, Kévin, et al.
Publicado: (2012)

Dynamic Reorganization of the Genome Shapes the Recombination Landscape in Meiotic Prophase
por: Patel, Lucas, et al.
Publicado: (2019)

Gain of DNA methylation is enhanced in the absence of CTCF at the human retinoblastoma gene promoter
por: Dávalos-Salas, Mercedes, et al.
Publicado: (2011)

An endosiRNA-Based Repression Mechanism Counteracts Transposon Activation during Global DNA Demethylation in Embryonic Stem Cells
por: Berrens, Rebecca V., et al.
Publicado: (2017)

Coupling shRNA screens with single-cell RNA-seq identifies a dual role for mTOR in reprogramming-induced senescence
por: Aarts, Marieke, et al.
Publicado: (2017)

Role of dynamic nuclear deformation on genomic architecture reorganization
por: Seirin-Lee, Sungrim, et al.
Publicado: (2019)

Cytoplasmic forces functionally reorganize nuclear condensates in oocytes
por: Al Jord, Adel, et al.
Publicado: (2022)

Clonality in haematopoietic stem cell ageing
por: Terradas-Terradas, Maria, et al.
Publicado: (2020)

DNA circles promote yeast ageing in part through stimulating the reorganization of nuclear pore complexes
por: Meinema, Anne C, et al.
Publicado: (2022)

Direct observation of nuclear reorganization driven by ultrafast spin transitions
por: Jiang, Yifeng, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_au0bf0dg1jmjjosk5fm1jt9s7k