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Immunomodulation of Selective Naive T Cell Functions by p110δ Inactivation Improves the Outcome of Mismatched Cell Transplantation

Allogeneic hematopoietic stem cell transplantation (HSCT) can treat certain hematologic malignancies due to the graft versus leukemia (GvL) effect but is complicated by graft versus host disease (GvHD). Expression of the p110δ catalytic subunit of the phosphoinositide 3-kinase pathway is restricted...

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Detalles Bibliográficos
Autores principales:	Doisne, Jean-Marc, Hüber, Christian M., Okkenhaug, Klaus, Colucci, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542309/ https://www.ncbi.nlm.nih.gov/pubmed/25660021 http://dx.doi.org/10.1016/j.celrep.2015.01.002

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