Single-Cell DNA Methylome Sequencing and Bioinformatic Inference of Epigenomic Cell-State Dynamics

Methods for single-cell genome and transcriptome sequencing have contributed to our understanding of cellular heterogeneity, whereas methods for single-cell epigenomics are much less established. Here, we describe a whole-genome bisulfite sequencing (WGBS) assay that enables DNA methylation mapping...

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Detalles Bibliográficos
Autores principales: Farlik, Matthias, Sheffield, Nathan C., Nuzzo, Angelo, Datlinger, Paul, Schönegger, Andreas, Klughammer, Johanna, Bock, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4542311/
https://www.ncbi.nlm.nih.gov/pubmed/25732828
http://dx.doi.org/10.1016/j.celrep.2015.02.001

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